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BOF: 62

A 62-year-old male presents with a history of discomfort in the upper abdomen, on the right hand side. He is a diet controlled diabetic, not on any medication. He smoked 10 cigarettes a day and used 14 units of alcohol per week.

On examination he was found to have an enlarged liver which was hard in consistency, the edge was craggy and the surface irregular. The spleen was not enlarged

Investigations

Hb 7.5 g/dL

WBC 22 x10⁹/L

Platelets 100 x10⁹/L

The blood film was reported as showing normoblasts, myeloblasts, myelocytes and metamyleocytes.

In this patient which of the following is most likely to account for the patient’s anaemia?

a)      Marrow infiltration by malignancy

b)      Acute myeloid leukaemia

c)      Chronic myeloid leukaemia

d)      Chronic lymphocytic leukaemia

e)      Myelofibrosis

 

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