BOF 59
Sickle cell anaemia, all are true, except:
1-despite the degree of anaemia in the chronic stable
state it is usually rarely symptomatic
2-in contrast to beta thalassaemia major, blood
transfusion is rarely indicated except probably in crisis or in certain
selected patients not in crisis
3-the target of blood transfusion is to raise the
haemoglobin A to 85-90% of the total haemoglobins and the PCV should be
between 30-36 %
4-pulmonary infarction-chest syndrome is the commonest
cause of death in adults
5-stroke in general is seen in 70 % of adults