BOF 49

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BOF: 49

An 80-year-old male is admitted with a history of feeling tired and lethargic and unable to fend for himself.

On examination he is noted to have generalised lymphadenopathy and an enlarged spleen.

Investigations

Hb 6.8 g/dL

WBC 30 x 10⁹ /L (94 % lymphocytes)

Platelets 55 x 10⁹/L

Blood film shows spherocytes

Reticulocytes 10%

In this patient which one of the following would you arrange to identify the cause of the patient’s anaemia?

a)      Osmotic fragility test

b)      Bone marrow examination

c)      Iron studies

d)      Coomb’s test

e)      Plasma protein electrophoresis

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